Solmaz Maleki Dizaj; Simin Sharifi; Shahriar Shahi; Soheila Montazersaheb; Sara Salatin; Elham Ahmadian; Khadijeh Khezri; Yalda Rahbar Saadat; Elaheh Dalir Abdolahinia; Mohammad Ali Ghavimi
Volume 4, Issue 2 , February 2022, , Pages 1224-136
Abstract
The main goal of this study was to gather the most critical bioactivities of curcumin, followed by the most essential concerns in its clinical usage and the challenges and potential ...
Read More
The main goal of this study was to gather the most critical bioactivities of curcumin, followed by the most essential concerns in its clinical usage and the challenges and potential for its use in modern medical studies. The conducted clinical studies on curcumin showed an effective anti-inflammatory and anti-cancer agent. The search results also revealed that curcumin has poor systemic bioavailability. Then, designing new methods to improve its bioavailability has always been interesting. Other conditions, such as neurodegenerative disease, cardiovascular disease, and diabetes, should be the subject of additional clinical research in the future. Besides, new procedures, such as adjuvants, drug delivery systems, and structural changes should be used in clinical trials of curcumin.